Phenolic profiling of Portuguese propolis by LC-MS spectrometry: uncommon propolis rich in flavonoid glycosides.
Identifieur interne : 002408 ( Main/Exploration ); précédent : 002407; suivant : 002409Phenolic profiling of Portuguese propolis by LC-MS spectrometry: uncommon propolis rich in flavonoid glycosides.
Auteurs : Soraia I. Falcão [Portugal] ; Nuno Vale ; Paula Gomes ; Maria R M. Domingues ; Cristina Freire ; Susana M. Cardoso ; Miguel Vilas-BoasSource :
- Phytochemical analysis : PCA [ 1099-1565 ]
Descripteurs français
- KwdFr :
- Chromatographie en phase liquide (instrumentation), Chromatographie en phase liquide (méthodes), Flavonoïdes (analyse), Flavonoïdes (composition chimique), Kaempférols (analyse), Marqueurs biologiques (analyse), Portugal (MeSH), Propolis (analyse), Propolis (composition chimique), Spectrométrie de masse ESI (méthodes), Structure moléculaire (MeSH).
- MESH :
- analyse : Flavonoïdes, Kaempférols, Marqueurs biologiques, Propolis.
- composition chimique : Flavonoïdes, Propolis.
- méthodes : Chromatographie en phase liquide, Spectrométrie de masse ESI.
- Chromatographie en phase liquide, Portugal, Structure moléculaire.
- Wicri :
- geographic : Portugal.
English descriptors
- KwdEn :
- Biomarkers (analysis), Chromatography, Liquid (instrumentation), Chromatography, Liquid (methods), Flavonoids (analysis), Flavonoids (chemistry), Kaempferols (analysis), Molecular Structure (MeSH), Portugal (MeSH), Propolis (analysis), Propolis (chemistry), Spectrometry, Mass, Electrospray Ionization (methods).
- MESH :
- chemical , analysis : Biomarkers, Flavonoids, Kaempferols, Propolis.
- chemical , chemistry : Flavonoids, Propolis.
- geographic : Portugal.
- instrumentation : Chromatography, Liquid.
- methods : Chromatography, Liquid, Spectrometry, Mass, Electrospray Ionization.
- Molecular Structure.
Abstract
INTRODUCTION
Propolis is a chemically complex resinous substance collected by honeybees (Apis mellifera) from tree buds, comprising plant exudates, secreted substances from bee metabolism, pollen and waxes. Its chemical composition depends strongly on the plant sources available around the beehive, which have a direct impact in the quality and bioactivity of the propolis. Being as Portugal is a country of botanical diversity, the phenolic characterisation of propolis from the different regions is a priority.
OBJECTIVE
Extensive characterisation of the phenolic composition of Portuguese propolis from different continental regions and islands.
METHOD
Forty propolis ethanolic extracts were analysed extensively by liquid chromatography with diode-array detection coupled to electrospray ionisation tandem mass spectrometry (LC-DAD-ESI-MS(n) ).
RESULTS
Seventy-six polyphenols were detected in the samples and two groups of propolis were established: the common temperate propolis, which contained the typical poplar phenolic compounds such as flavonoids and their methylated/esterified forms, phenylpropanoid acids and their esters, and an uncommon propolis type with an unusual composition in quercetin and kaempferol glycosides - some of them never described in propolis.
CONCLUSION
The method allowed the establishment of the phenolic profile of Portuguese propolis from different geographical locations, and the possibility to use some phenolic compounds, such as kaempferol-dimethylether, as geographical markers. Data suggest that other botanical species in addition to poplar trees can be important sources of resins for Portuguese propolis.
DOI: 10.1002/pca.2412
PubMed: 23172843
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Apolónia, Apartado 1172, 5301-855 Bragança</wicri:regionArea><wicri:noRegion>5301-855 Bragança</wicri:noRegion></affiliation></author><author><name sortKey="Vale, Nuno" sort="Vale, Nuno" uniqKey="Vale N" first="Nuno" last="Vale">Nuno Vale</name></author><author><name sortKey="Gomes, Paula" sort="Gomes, Paula" uniqKey="Gomes P" first="Paula" last="Gomes">Paula Gomes</name></author><author><name sortKey="Domingues, Maria R M" sort="Domingues, Maria R M" uniqKey="Domingues M" first="Maria R M" last="Domingues">Maria R M. Domingues</name></author><author><name sortKey="Freire, Cristina" sort="Freire, Cristina" uniqKey="Freire C" first="Cristina" last="Freire">Cristina Freire</name></author><author><name sortKey="Cardoso, Susana M" sort="Cardoso, Susana M" uniqKey="Cardoso S" first="Susana M" last="Cardoso">Susana M. Cardoso</name></author><author><name sortKey="Vilas Boas, Miguel" sort="Vilas Boas, Miguel" uniqKey="Vilas Boas M" first="Miguel" last="Vilas-Boas">Miguel Vilas-Boas</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013 Jul-Aug</date><idno type="RBID">pubmed:23172843</idno><idno type="pmid">23172843</idno><idno type="doi">10.1002/pca.2412</idno><idno type="wicri:Area/Main/Corpus">002799</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">002799</idno><idno type="wicri:Area/Main/Curation">002799</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">002799</idno><idno type="wicri:Area/Main/Exploration">002799</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Phenolic profiling of Portuguese propolis by LC-MS spectrometry: uncommon propolis rich in flavonoid glycosides.</title><author><name sortKey="Falcao, Soraia I" sort="Falcao, Soraia I" uniqKey="Falcao S" first="Soraia I" last="Falcão">Soraia I. Falcão</name><affiliation wicri:level="1"><nlm:affiliation>CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Sta. Apolónia, Apartado 1172, 5301-855 Bragança, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Sta. Apolónia, Apartado 1172, 5301-855 Bragança</wicri:regionArea><wicri:noRegion>5301-855 Bragança</wicri:noRegion></affiliation></author><author><name sortKey="Vale, Nuno" sort="Vale, Nuno" uniqKey="Vale N" first="Nuno" last="Vale">Nuno Vale</name></author><author><name sortKey="Gomes, Paula" sort="Gomes, Paula" uniqKey="Gomes P" first="Paula" last="Gomes">Paula Gomes</name></author><author><name sortKey="Domingues, Maria R M" sort="Domingues, Maria R M" uniqKey="Domingues M" first="Maria R M" last="Domingues">Maria R M. Domingues</name></author><author><name sortKey="Freire, Cristina" sort="Freire, Cristina" uniqKey="Freire C" first="Cristina" last="Freire">Cristina Freire</name></author><author><name sortKey="Cardoso, Susana M" sort="Cardoso, Susana M" uniqKey="Cardoso S" first="Susana M" last="Cardoso">Susana M. Cardoso</name></author><author><name sortKey="Vilas Boas, Miguel" sort="Vilas Boas, Miguel" uniqKey="Vilas Boas M" first="Miguel" last="Vilas-Boas">Miguel Vilas-Boas</name></author></analytic><series><title level="j">Phytochemical analysis : PCA</title><idno type="eISSN">1099-1565</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomarkers (analysis)</term><term>Chromatography, Liquid (instrumentation)</term><term>Chromatography, Liquid (methods)</term><term>Flavonoids (analysis)</term><term>Flavonoids (chemistry)</term><term>Kaempferols (analysis)</term><term>Molecular Structure (MeSH)</term><term>Portugal (MeSH)</term><term>Propolis (analysis)</term><term>Propolis (chemistry)</term><term>Spectrometry, Mass, Electrospray Ionization (methods)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Chromatographie en phase liquide (instrumentation)</term><term>Chromatographie en phase liquide (méthodes)</term><term>Flavonoïdes (analyse)</term><term>Flavonoïdes (composition chimique)</term><term>Kaempférols (analyse)</term><term>Marqueurs biologiques (analyse)</term><term>Portugal (MeSH)</term><term>Propolis (analyse)</term><term>Propolis (composition chimique)</term><term>Spectrométrie de masse ESI (méthodes)</term><term>Structure moléculaire (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Biomarkers</term><term>Flavonoids</term><term>Kaempferols</term><term>Propolis</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Flavonoids</term><term>Propolis</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Portugal</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Flavonoïdes</term><term>Kaempférols</term><term>Marqueurs biologiques</term><term>Propolis</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Flavonoïdes</term><term>Propolis</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Chromatography, Liquid</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Chromatography, Liquid</term><term>Spectrometry, Mass, Electrospray Ionization</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Chromatographie en phase liquide</term><term>Spectrométrie de masse ESI</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Molecular Structure</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Chromatographie en phase liquide</term><term>Portugal</term><term>Structure moléculaire</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Portugal</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b></p><p>Propolis is a chemically complex resinous substance collected by honeybees (Apis mellifera) from tree buds, comprising plant exudates, secreted substances from bee metabolism, pollen and waxes. Its chemical composition depends strongly on the plant sources available around the beehive, which have a direct impact in the quality and bioactivity of the propolis. Being as Portugal is a country of botanical diversity, the phenolic characterisation of propolis from the different regions is a priority.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>Extensive characterisation of the phenolic composition of Portuguese propolis from different continental regions and islands.</p></div><div type="abstract" xml:lang="en"><p><b>METHOD</b></p><p>Forty propolis ethanolic extracts were analysed extensively by liquid chromatography with diode-array detection coupled to electrospray ionisation tandem mass spectrometry (LC-DAD-ESI-MS(n) ).</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Seventy-six polyphenols were detected in the samples and two groups of propolis were established: the common temperate propolis, which contained the typical poplar phenolic compounds such as flavonoids and their methylated/esterified forms, phenylpropanoid acids and their esters, and an uncommon propolis type with an unusual composition in quercetin and kaempferol glycosides - some of them never described in propolis.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>The method allowed the establishment of the phenolic profile of Portuguese propolis from different geographical locations, and the possibility to use some phenolic compounds, such as kaempferol-dimethylether, as geographical markers. Data suggest that other botanical species in addition to poplar trees can be important sources of resins for Portuguese propolis.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23172843</PMID><DateCompleted><Year>2014</Year><Month>02</Month><Day>04</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1099-1565</ISSN><JournalIssue CitedMedium="Internet"><Volume>24</Volume><Issue>4</Issue><PubDate><MedlineDate>2013 Jul-Aug</MedlineDate></PubDate></JournalIssue><Title>Phytochemical analysis : PCA</Title><ISOAbbreviation>Phytochem Anal</ISOAbbreviation></Journal><ArticleTitle>Phenolic profiling of Portuguese propolis by LC-MS spectrometry: uncommon propolis rich in flavonoid glycosides.</ArticleTitle><Pagination><MedlinePgn>309-18</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/pca.2412</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Propolis is a chemically complex resinous substance collected by honeybees (Apis mellifera) from tree buds, comprising plant exudates, secreted substances from bee metabolism, pollen and waxes. Its chemical composition depends strongly on the plant sources available around the beehive, which have a direct impact in the quality and bioactivity of the propolis. Being as Portugal is a country of botanical diversity, the phenolic characterisation of propolis from the different regions is a priority.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Extensive characterisation of the phenolic composition of Portuguese propolis from different continental regions and islands.</AbstractText><AbstractText Label="METHOD" NlmCategory="METHODS">Forty propolis ethanolic extracts were analysed extensively by liquid chromatography with diode-array detection coupled to electrospray ionisation tandem mass spectrometry (LC-DAD-ESI-MS(n) ).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Seventy-six polyphenols were detected in the samples and two groups of propolis were established: the common temperate propolis, which contained the typical poplar phenolic compounds such as flavonoids and their methylated/esterified forms, phenylpropanoid acids and their esters, and an uncommon propolis type with an unusual composition in quercetin and kaempferol glycosides - some of them never described in propolis.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The method allowed the establishment of the phenolic profile of Portuguese propolis from different geographical locations, and the possibility to use some phenolic compounds, such as kaempferol-dimethylether, as geographical markers. Data suggest that other botanical species in addition to poplar trees can be important sources of resins for Portuguese propolis.</AbstractText><CopyrightInformation>Copyright © 2012 John Wiley & Sons, Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Falcão</LastName><ForeName>Soraia I</ForeName><Initials>SI</Initials><AffiliationInfo><Affiliation>CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Sta. Apolónia, Apartado 1172, 5301-855 Bragança, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vale</LastName><ForeName>Nuno</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Gomes</LastName><ForeName>Paula</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Domingues</LastName><ForeName>Maria R M</ForeName><Initials>MR</Initials></Author><Author ValidYN="Y"><LastName>Freire</LastName><ForeName>Cristina</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Cardoso</LastName><ForeName>Susana M</ForeName><Initials>SM</Initials></Author><Author ValidYN="Y"><LastName>Vilas-Boas</LastName><ForeName>Miguel</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>11</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Phytochem Anal</MedlineTA><NlmUniqueID>9200492</NlmUniqueID><ISSNLinking>0958-0344</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C464827">3,4'-dimethylkaempferol</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005419">Flavonoids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D044949">Kaempferols</NameOfSubstance></Chemical><Chemical><RegistryNumber>9009-62-5</RegistryNumber><NameOfSubstance UI="D011429">Propolis</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002853" MajorTopicYN="N">Chromatography, Liquid</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005419" MajorTopicYN="N">Flavonoids</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D044949" MajorTopicYN="N">Kaempferols</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015394" MajorTopicYN="N">Molecular Structure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011174" MajorTopicYN="N" Type="Geographic">Portugal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011429" MajorTopicYN="N">Propolis</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D021241" MajorTopicYN="N">Spectrometry, Mass, Electrospray Ionization</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>05</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2012</Year><Month>10</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>10</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>11</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>11</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>2</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23172843</ArticleId><ArticleId IdType="doi">10.1002/pca.2412</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Portugal</li></country></list><tree><noCountry><name sortKey="Cardoso, Susana M" sort="Cardoso, Susana M" uniqKey="Cardoso S" first="Susana M" last="Cardoso">Susana M. Cardoso</name><name sortKey="Domingues, Maria R M" sort="Domingues, Maria R M" uniqKey="Domingues M" first="Maria R M" last="Domingues">Maria R M. Domingues</name><name sortKey="Freire, Cristina" sort="Freire, Cristina" uniqKey="Freire C" first="Cristina" last="Freire">Cristina Freire</name><name sortKey="Gomes, Paula" sort="Gomes, Paula" uniqKey="Gomes P" first="Paula" last="Gomes">Paula Gomes</name><name sortKey="Vale, Nuno" sort="Vale, Nuno" uniqKey="Vale N" first="Nuno" last="Vale">Nuno Vale</name><name sortKey="Vilas Boas, Miguel" sort="Vilas Boas, Miguel" uniqKey="Vilas Boas M" first="Miguel" last="Vilas-Boas">Miguel Vilas-Boas</name></noCountry><country name="Portugal"><noRegion><name sortKey="Falcao, Soraia I" sort="Falcao, Soraia I" uniqKey="Falcao S" first="Soraia I" last="Falcão">Soraia I. Falcão</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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